Pomegranate extract inhibits androgen-independent prostate cancer growth

This interesting study from Molecular Cancer Therapeutics documents the inhibition of prostate cancer cell proliferation and the induction of apoptosis (cell death) with pomegranate extract. Of special importance is the described association with chronic inflammation driven by nuclear factor-κB (NF-κB) activity. This is involved in the transition from androgen dependence of prostate cancer cells to ones that no longer depend on male hormone stimulation. Pomegranate extract is shown to help reduce this inflammatory process.