Oral DMSA for elimination of toxic metals with autistic spectrum disorders

This research  on the safety and efficacy of oral DMSA (dimercapto succinic acid) therapy for children with autistic spectrum disorders was recently published in BMC Clinical Pharmacology in two parts:

  1. Part A—Medical results
  2. Part B—Behavioral results

The authors conclude in Part A: "Overall, DMSA therapy seems to be reasonably safe, effective in removing several toxic metals (especially lead), dramatically effective in normalizing RBC glutathione, and effective in normalizing platelet counts. Only 1 round (3 days) was sufficient to improve glutathione and platelets. Additional rounds increased excretion of toxic metals."They further state in their conclusion to Part B: "Overall, both one and seven rounds of DMSA therapy seems to be reasonably safe in children with ASD who have high urinary excretion of toxic metals, and possibly helpful in reducing some of the symptoms of autism in those children." [RBC = red blood cell; ASD = autistic spectrum disorder]

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