Lifestyle beats metformin for diabetes prevention

The 10-year follow-up of diabetes and weight loss in the Diabetes Prevention Program Outcomes Study was reported in a paper published recently in The Lancet. The authors state that "Diabetes incidence in the 10 years since DPP randomisation was reduced by 34%...in the lifestyle group and 18%...in the metformin group compared with placebo." It has been my experience that, although evidence-based nutraceuticals and medications have an important role, lifestyle factors including diet and exercise carry the greatest weight. Also hear this story on the impact of lifestyle changes reported on NPR.