FUNCTIONAL MEDICINE BLOG
Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.
Leaky gut: inflammation, chronic fatigue and depression
Leaky gut permits bacterial LPS translocation into the gut lymphoid tissue where it triggers inflammation causing chronic fatigue and depression.
Fatigue: inflammation and autoimmunity
Severe fatigue, associated with chronic fatigue syndrome (CFS) or another disorder, has as a core underlying cause chronic inflammation...there are sufficient robust multiple lines of evidence to support the proposition that the severe fatigue and profound disability experienced by people with the neurodegenerative, neuro-immune and autoimmune diseases discussed here is largely driven by peripheral immune activation and systemic inflammation either directly or indirectly by inducing mitochondrial damage.
Chronic fatigue is experienced through the brain
An important study just published in PLOS One reveals a primary mechanism by which the fatigue of chronic fatigue syndrome (CFS) is experienced in the brain, and that this is associated with immune inflammatory activation.
Neuropsychiatric illness, autoimmunity and the role of microbes
Neuropsychiatric illness often involves brain inflammation for which there may be an autoimmune origin. The authors of a paper* recently published in Current Opinion in Rheumatology set out to..."illustrate how microbes might participate in the pathogenesis of neuropsychiatric illness by triggering the production of autoantibodies that bind to brain targets."
Prof. Y. Shoenfeld talks about ASIA: autoimmune syndrome induced by vaccine adjuvants
Professor Yehuda Shoenfeld of the Zabludowicz Center for Autoimmune Diseases, Tel-Aviv University talks on ASIA—autoimmune sydrome induced by adjuvants (used to magnify the immune response to vaccines). He does not argue against the immense benefits of vaccines, but explains briefly why clinicians must be aware of the potential for autoimmune complications in a percentage of the population that may be predisposed. Morever, he discusses how the process in ASIA is relevant also for the loss of tolerance involved in conditions such as environmental and chemical sensitivity, chronic fatigue syndrome (CFS), fibromyalgia, narcolepsy, sick building syndrome, reactions to silicon implants, Gulf War syndrome and others.
Chronic Fatigue Syndrome treated as an immunological disorder
Chronic Fatigue Syndrome treated as an immunological disorder
How the Microbiome causes Autoimmune Dysfunction
How the Microbiome causes Autoimmune Dysfunction