FUNCTIONAL MEDICINE BLOG
Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.
Leaky gut: inflammation, chronic fatigue and depression
Leaky gut permits bacterial LPS translocation into the gut lymphoid tissue where it triggers inflammation causing chronic fatigue and depression.
Autoimmune inflammation can elevate serum 1,25-dihydroxy vitamin D
I have found that patients with an autoimmune component to their case often have elevated 1,25-dihydroxy vitamin D (calcitriol). This is not the 25-hydroxy vitamin D3 (cholecalciferol metabolite) that we always test to determine vitamin D3 sufficiency. Often with normal and even low vitamin D3 levels, patients with various degrees of active autoimmunity are testing for elevated 1,25-dihydroxy vitamin D levels. Now research published in PLOS One (Public Library of Science) shows how autoimmune inflammation and elevated 1,25-dihydroxy vitamin D are associated.
Depression, aging and brain inflammation: indications for sustainable treatment
Depression and aging, not only diminished cognitive function but the level of physiological competence throughout the body, have brain inflammation in common. This fact is of premiere importance when designing rational treatment plans for both depression and high functioning longevity.