FUNCTIONAL MEDICINE BLOG
Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.
Fatigue: inflammation and autoimmunity
Severe fatigue, associated with chronic fatigue syndrome (CFS) or another disorder, has as a core underlying cause chronic inflammation...there are sufficient robust multiple lines of evidence to support the proposition that the severe fatigue and profound disability experienced by people with the neurodegenerative, neuro-immune and autoimmune diseases discussed here is largely driven by peripheral immune activation and systemic inflammation either directly or indirectly by inducing mitochondrial damage.
Chronic fatigue is experienced through the brain
An important study just published in PLOS One reveals a primary mechanism by which the fatigue of chronic fatigue syndrome (CFS) is experienced in the brain, and that this is associated with immune inflammatory activation.
Inflammation, mitochondrial dysfunction and neurodegeneration in major depression
Inflammation, mitochondrial dysfunction and neurodegeneration in major depression