Bisphosphonates adversely affect orthodontic treatment

Bisphosphonates are drugs used to increase bone density by killing off the cells that resorb old bone (osteoclasts) to 'make room' for new bone cells. Bisphosphonates include alendronate (Fosamax and Binosto), zoledronic acid (Reclast), risedronate (Actonel) and ibandronate (Boniva)...A study just published in the American Journal of Orthodontics & Dentofacial Orthopedics documents adverse effects of bisphosphonates on orthodontic outcomes.