FUNCTIONAL MEDICINE BLOG
Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.
Gut microbiome, SCFAs, mood disorders, ketogenic diet and seizures
SCFA (short-chain fatty acid) production by the gut microbiome has a large effect on autoimmunity, brain inflammation, neuropsychiatric disorders and seizures by Immune system modulation; and this positive effect can be damaged by antibiotics.
Antibiotics can adversely alter gut microbiome for a year
The fecal microbiome was severely affected by most antibiotics: for months, health-associated butyrate-producing species became strongly underrepresented...Clearly, even a single antibiotic treatment in healthy individuals contributes to the risk of resistance development and leads to long-lasting detrimental shifts in the gut microbiome.
Epilepsy as an autoimmune disorder
Epilepsy should be evaluated in case management for neuroinflammation that reduces neuronal thresholds of excitability, and more evidence that this can be due to autoimmunity was just published in JAMA Neurology.
Histamine intolerance
Histamine intolerance is a widespread phenomenon that can mimic allergy. It plays a role in many diverse conditions including IBS and inflammatory bowel diseases, asthma, postural orthostatic tachycardia syndrome (POTS), complications of pregnancy, drug hypersensitivity, and intestinal permeability (by means of which it contributes to autoimmunity). It can be objectively evaluated with serum DAO activity. HI can be ameliorated by supplementation with DAO. Practitioners need to be astute in its diagnosis and management.
Inflammatory bowel disease is associated with childhood antibiotic exposure
Inflammatory bowel disease includes ulcerative colitis and Crohn's disease where the immune system attacks the large intestine and small intestine respectively. Considering the emerging science on the profound importance of the human micro biome for immune system maturation, regulation and tolerance, a study just published in the journal Pediatrics offering evidence that antibiotic exposure in childhood is associated with inflammatory bowel disease comes as no surprise.
Acute gastrointestinal infection can turn on autoimmune disorders
Autoimmune disorders can be promoted by a variety of factors that must be considered in case management.Acute gastrointestinal infection—such as a food-borne illness or viral gastroenteritis—can cause the immune system to lose tolerance for commensal bacteria (the ones that normally live in the intestines), contributing to the development of autoimmune disorders.
Apple polyphenols each day may help keep intestinal inflammation away
Apple polyphenols each day may help keep intestinal inflammation away
Therapeutic resources for inflammatory bowel disease
Therapeutic resources for inflammatory bowel disease
Beneficial E. coli helps heal ulcerative colitis
Beneficial E. coli helps heal ulcerative colitis
RDW is an inexpensive but powerful indicator often overlooked on your routine blood test
RDW is an inexpensive but powerful indicator often overlooked on your routine blood test
Resveratrol relieves inflammation in the colon
Resveratrol relieves inflammation in the colon