Insulin receptor expression by human prostate cancers

There's much more to prostate cancer prevention than finasteride. Here is another recent study published in the journal Prostate that documents the presence of insulin receptors on primary human prostate cancers. "The findings are relevant..to the hypothesis that obesity-associated hyperinsulinemia mediates the adverse effect of obesity on prostate cancer prognosis." Important: Finasteride works by blocking the enzyme that converts testosterone to the more potent metabolite dihydrotestosterone. It, and natural agents that also inhibit the same enzyme, are helpful if dihydrotestosterone is too high—but this is not always the case. Lowering it too much can result in common adverse reactions that include decreased libido, impotence, and decreased ejaculatory volume. The functional approach to prostate disorders always includes lab assessment of the biologically active free fraction testosterone, dihydrotestosterone, estradiol, and the pituitary hormones LH and FSH that stimulate their production.