11/20/18 11/20/18

Antigliadin antibodies harmful for brain at low levels

Antigliadin antibodies (AGA), a subset of anti-gluten antibodies, have been shown to be harmful to the brain at levels below the standard reference range in an important study on gluten ataxia (GA) published in the journal Nutrients. Gluten ataxia is a condition characterized by loss of balance due to cerebellar damage due to neuroinflammation provoked by gluten. Non-celiac gluten sensitivity (NCGS) can cause inflammation in the brian and central nervous with antibodies at lower levels than in celiac disease and in the absence of abdominal symptoms.

5/14/15 5/14/15

ALS and gluten sensitivity

In a study just published in JAMA Neurology, investigators report an association between some cases of ALS (amyotrophic lateral sclerosis) and gluten sensitivity.

4/23/15 4/23/15

Gluten intolerance acquired after gastroenteritis

Gluten intolerance can occur at any age due to a number of causes that contribute to loss of immune tolerance. The authors of a paper published recently in the journal Gastroenterology and Hepatology from Bed to Bench remind how a bout of viral or bacterial gastroenteritis can be the trigger.

3/16/15 3/16/15

Intestinal barrier damage from food additives and pesticides

1/10/15 1/10/15

Gluten free labeled foods not always gluten free

Gluten free labeling is, sadly, not a guarantee of safety for those with celiac disease or non-celiac gluten sensitivity as demonstrated in a study recently published in the Journal of Food Protection.

8/27/14 8/27/14

Depression and brain inflammation

Evidence for the role of brain inflammation in depression is proliferating as noted in a report published recently in JAMA. Certain biomarkers including the proinflammatory cytokines interleukin-6 (IL-6) and TNF, and CRP are standing out...

2/27/14 2/27/14

Bipolar disorder and neuroinflammation

There is a massive amount of evidence supporting the importance of assessing and treating neuroinflammation in bipolar disorder and other neuropsychiatric illnesses. This makes necessarily the comprehensive examination of autoimmunity and its numerous underlying contributory causes.

11/5/13 11/5/13

Hyperexcitable brain syndrome and gluten

Hyperexcitable brain, with potentially severe consequences, is recognized as among the gluten-related autoiimmune neurological disorders... Practitioners should not underestimate the potential severity of gluten-associated neuroinflammation.

10/1/13 10/1/13

Food allergy testing with IgG4 is not recommended

"...food-specific IgG4 does not indicate (imminent) food allergy or intolerance, but rather a physiological response of the immune system after exposition to food components. Therefore, testing of IgG4 to foods is considered as irrelevant for the laboratory work-up of food allergy or intolerance and should not be performed in case of food-related complaints."

2/26/13 2/26/13

Non-celiac gluten sensitivity

Celiac disease is but one consequence of autoimmunity or autoinflammation triggered by gluten among a host of others better characterized by the term non-celiac gluten sensitivity (NCGS). The lack of standardization in terminology has obscured this fact, so two recent papers that help to clear the air are welcome.