1/4/18 1/4/18

Vagus nerve regulates inflammation and metabolism

5/31/17 5/31/17

Subclinical hypothyroidism worsens cardiometabolic profile

4/17/17 4/17/17

Prediabetes, chronic inflammation and hemoglobin A1c

11/1/16 11/1/16

Levothyroxine therapy and normal TSH yet hypothyroid symptoms

A significant proportion of patients treated with levothyroxine continue to experience residual symptoms of hypothyroidism, including psychological and metabolic effects, due to inadequate conversion of T4 to T3.

4/6/14 4/6/14

Thyroid in heart, metabolism, brain, kidney; vital importance of T3

Thyroid disorders have widespread impact and although subclinical hypothyroidism and low triiodothyronine (T3) syndrome are common they are frequently overlooked in practice.

10/20/13 10/20/13

Metabolic health status and aging determined by inflammation, not weight

Metabolic health is not reliably determined by weight or BMI (body mass index). Lean individuals can suffer from cardiovascular and other diseases involving metabolism, and evidence has been mounting that supports the notion of a subtype of obesity that is metabolically healthy. Inflammation can determine metabolic health in both obese and non-obese populations.

3/3/13 3/3/13

High protein beats high carbohydrate diet for biomarkers of metabolic syndrome

Regulating insulin is the key factor metabolic syndrome, diabetes and weight loss. In accordance with that, a randomized controlled trial just published in the journal Diabetes Care offers more evidence that a higher protein (with carbohydrate) diet improves multiple biomarkers better than a high carbohydrate diet.

2/28/13 2/28/13

Sugar calories are worse for diabetes and obesity than others

Attentive clinicians who have been exhorting their patients for years to avoid excessively stimulating insulin production with sugar are heartily welcoming the superb research just published in PLoS One (Public Library of Science) that drives a stake through the heart of the mistaken notions that calories from sugar have the same effect as others, and that obesity causes diabetes.

2/17/13 2/17/13

Weight loss and insulin resistance improved by branched-chain amino acids

Weight loss and improvement in insulin resistance naturally go hand in hand, and a study just published in the journal Diabetologia confirms that consumption of branched-chain amino acids (BCAAs) helps both. Isoleucine, leucine and valine are already known to promote muscle growth and repair, influence brain signaling for appetite and metabolic rate, help with burn recovery, and be remedial for autism when it includes genetic mutations in BCAA pathways.