FUNCTIONAL MEDICINE BLOG 

Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.

Hormone replacement in menopause and ovarian cancer risk

Hormone replacement in menopause must be evaluated thoroughly on an individual basis with careful attention to the important benefits and risks. This includes of course objective measurements of bioactive hormone levels before and during hormone replacement at appropriate intervals, including analysis of benign versus troublesome estrogen metabolites. Regarding adverse effects that must be weighed, an important study just published in The Lancet brings to light a significant risk for ovarian cancer in current and past users of hormone replacement.

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Calcium supplementation and abnormal calcium in blood and urine

Calcium supplementation is often recommended without careful determination of individual need and tolerance. Conflicting studies have raised the suspicion of an increase in cardiovascular risk associated with calcium (which may occur when the anti-inflammatory effects of magnesium are opposed). A study just published in the journal Menopause offers evidence that for a significant percentage of women modest calcium supplementation produces abnormally high levels in blood (hypercalcemia) and urine (hypercalciuria).

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