FUNCTIONAL MEDICINE BLOG
Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.
Levothyroxine therapy and normal TSH yet hypothyroid symptoms
A significant proportion of patients treated with levothyroxine continue to experience residual symptoms of hypothyroidism, including psychological and metabolic effects, due to inadequate conversion of T4 to T3.
Mood disorders and thyroid autoimmunity
Mood disorders and thyroid autoimmunity are linked by aberrant levels of hematopoietic/neuronal growth factors...even before hypothyroidism has developed, and also in relatives of thyroid autoimmunity subjects, growth factors necessary for healthy brain function are at levels associated with a range of mood disorders including bipolar, depression and psychosis. They also include an important reminder that antibodies can predict clinical disease years in advance.