FUNCTIONAL MEDICINE BLOG
Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.
Gut microbiome, SCFAs, mood disorders, ketogenic diet and seizures
SCFA (short-chain fatty acid) production by the gut microbiome has a large effect on autoimmunity, brain inflammation, neuropsychiatric disorders and seizures by Immune system modulation; and this positive effect can be damaged by antibiotics.
Osteoarthritis: auto-inflammation, IL-17 and the microbiome
Osteoarthritis is an autoinflammatory condition characterized by a more aggressive inflammatory response to stressed or damaged tissue, with a subset exhibiting high IL-17 activity, a hallmark of autoimmunity. This may be ameliorated by regulating the autoinflammatory response through manipulation of the gut microbiome.
Circadian rhythms of inflammation
Treatment of chronic inflammation can be enhanced and adrenal suppression minimized by circadian dosing of anti-inflammatory medication.
Women's heart risk lower with exercise 2-3x/week than daily
A large study using data from 1.1 million women recently published in the journal Circulation offers evidence that strenuous physical activity 2-3 times per week significantly lowered their coronary heart disease risk while more frequent strenuous exercise actually increased it.
Hair loss frequently associated with autoimmunity
Identifying hair loss as associated with early immune system dysregulation not only permits proper treatment of the presenting complaint but becomes an opportunity to ward off progression to more debilitating autoimmune disease.
Acne, a disorder of dysregulated inflammation
Acne vulgaris case management with sustainable, functional methods requires its recognition as a disorder of inflammation associated with loss of immune tolerance for a commensal skin bacteria.
Migraine and histamine intolerance, with a link to MS
Histamine is involved in the pathogenesis of both migraine and multiple sclerosis (NS).
Depression, aging and brain inflammation: indications for sustainable treatment
Depression and aging, not only diminished cognitive function but the level of physiological competence throughout the body, have brain inflammation in common. This fact is of premiere importance when designing rational treatment plans for both depression and high functioning longevity.
The autoimmune aspect of cardiovascular disease and Th17/Treg imbalance
The autoimmune aspect of cardiovascular disease and Th17/Treg imbalance