FUNCTIONAL MEDICINE BLOG 

Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.

Metabolic health status and aging determined by inflammation, not weight

Metabolic health is not reliably determined by weight or BMI (body mass index). Lean individuals can suffer from cardiovascular and other diseases involving metabolism, and evidence has been mounting that supports the notion of a subtype of obesity that is metabolically healthy. Inflammation can determine metabolic health in both obese and non-obese populations.

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Vagal nerve activity moderates brain-immune relationships and is measured by heart rate variability

An exciting study with tremendous practical significance was just published in the Journal of Neuroimmunology that shows how vagal nerve activity, which can be measured in the clinic by heart rate variability analysis (HRV), is a key moderator of the brain-immune web and determines the immune and physiological responses to acute stress.

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Cardiovascular Cardiovascular

Aspirin Cardiovascular/Gastrointestinal Risk Calculator

Aspirin has been shown to be worthy of consideration for secondary, and in some cases primary, prevention of heart attacks and strokes but carries known risks for gastrointestinal side effects. If you're not certain whether to recommend low-dose aspirin to a patient, the aspirin cardiovascular/gastrointestinal risk calculator can help with the clinical decision. A paper recently published in the journal Alimentary Pharmacology and Therapeutics describes the development and use of this practical tool.

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