10/11/18 10/11/18

Gut microbiome, SCFAs, mood disorders, ketogenic diet and seizures

SCFA (short-chain fatty acid) production by the gut microbiome has a large effect on autoimmunity, brain inflammation, neuropsychiatric disorders and seizures by Immune system modulation; and this positive effect can be damaged by antibiotics.

6/8/14 6/8/14

Neuropsychiatric illness in non-celiac gluten sensitivity

Neuropsychiatric illness can result from neuroinflammation due to a variety of causes. Recent studies offer more evidence that depression and other neuropsychiatric disorders can be a manifestation of non-celiac gluten sensitivity. A paper published in Gastroenterology Research and Practice explores the pathophysiologic mechanisms by which gluten sensitivity can present as a variety of neuropsychiatric conditions in the absence of celiac disease.

4/9/14 4/9/14

Epilepsy as an autoimmune disorder

Epilepsy should be evaluated in case management for neuroinflammation that reduces neuronal thresholds of excitability, and more evidence that this can be due to autoimmunity was just published in JAMA Neurology.

3/10/14 3/10/14

SSRIs (selective serotonin reuptake inhibitors) may prolong seizures

11/17/13 11/17/13

Cognitive decline: major overlooked causes

Cognitive decline is fueled by that have not received adequate attention but have great practical, clinical significance.

11/5/13 11/5/13

Hyperexcitable brain syndrome and gluten

Hyperexcitable brain, with potentially severe consequences, is recognized as among the gluten-related autoiimmune neurological disorders... Practitioners should not underestimate the potential severity of gluten-associated neuroinflammation.

11/4/12 11/4/12

Lyme disease, neuropsychiatric symptoms and autoimmunity

As with other chronic infections, the most devastating effects of Lyme disease can occur from the immune system losing tolerance for normal tissue as it cross-reacts while attacking the pathogen. A paper just published in The Open Neurology Journal reviews the body of knowledge on the neuropsychiatric symptoms of Lyme disease and other infections as an immune mediated neurodegenerative disorder, enlarged by a wealth of citations.