Dr. Jonathan Miller 4/17/23 Dr. Jonathan Miller 4/17/23

Oral contraceptive hormone doses could be reduced by over 90%

“Results show that it is possible to reduce the total dose by 92% in estrogen monotherapy, 43% in progesterone monotherapy, and…that by combining estrogen and progesterone the dose can be lowered even more.”

5/14/18 5/14/18

Estrogen's contribution to autoimmune inflammation

5/14/18 5/14/18

Estrogen's contribution to autoimmune inflammation

2/12/16 2/12/16

Postmenopausal vaginal atrophy relieved by fennel cream

Fennel cream effectively treats postmenopausal vaginal atrophy without side effects.

4/20/15 4/20/15

Fatigue: inflammation and autoimmunity

Severe fatigue, associated with chronic fatigue syndrome (CFS) or another disorder, has as a core underlying cause chronic inflammation...there are sufficient robust multiple lines of evidence to support the proposition that the severe fatigue and profound disability experienced by people with the neurodegenerative, neuro-immune and autoimmune diseases discussed here is largely driven by peripheral immune activation and systemic inflammation either directly or indirectly by inducing mitochondrial damage.

2/22/15 2/22/15

Hormone replacement in menopause and ovarian cancer risk

Hormone replacement in menopause must be evaluated thoroughly on an individual basis with careful attention to the important benefits and risks. This includes of course objective measurements of bioactive hormone levels before and during hormone replacement at appropriate intervals, including analysis of benign versus troublesome estrogen metabolites. Regarding adverse effects that must be weighed, an important study just published in The Lancet brings to light a significant risk for ovarian cancer in current and past users of hormone replacement.

9/26/13 9/26/13

Progesterone and irritable bowel syndrome, headaches and irritable bladder

Progesterone plays a role in preventing or ameliorating irritable bowel syndrome by inhibiting the release of histamine. This applies to numerous conditions including migraine, interstitial cystitis (painful/irritable bladder), dysmenorrhea and others.