FUNCTIONAL MEDICINE BLOG
Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.
Gut microbiome, SCFAs, mood disorders, ketogenic diet and seizures
SCFA (short-chain fatty acid) production by the gut microbiome has a large effect on autoimmunity, brain inflammation, neuropsychiatric disorders and seizures by Immune system modulation; and this positive effect can be damaged by antibiotics.
Fasting insulin reliably shows insulin resistance
Insulin resistance can be reliably shown by fasting plasma insulin levels above 10.7 μU/ml.
Migraine, depression, Alzheimer's and lipid metabolism
"Taken together, our findings suggest it is possible that migraine is a neurologic disorder of 'minor' sphingolipid dysmetabolism..."
Prediabetes increases cancer risk
Prediabetes, elevated levels of blood sugar that are still 'within' the normal range, increases cancer risk among its mob of other afflictions as further validated by a meta-analysis just published in Diabetologia.
Nigella sativa, a true 'wonder medicine'?
Nigella sativa, also known as black cumin, produces seeds with a mind-boggling wealth of medicinal virtues. For colleagues and others who may not be familiar with the abundance of scientific evidence for the use of Nigella sativa seed extract in clinical practice, this selection of citations serves as an introduction to its wide range of indications.
Thyroid in heart, metabolism, brain, kidney; vital importance of T3
Thyroid disorders have widespread impact and although subclinical hypothyroidism and low triiodothyronine (T3) syndrome are common they are frequently overlooked in practice.
High protein beats high carbohydrate diet for biomarkers of metabolic syndrome
Regulating insulin is the key factor metabolic syndrome, diabetes and weight loss. In accordance with that, a randomized controlled trial just published in the journal Diabetes Care offers more evidence that a higher protein (with carbohydrate) diet improves multiple biomarkers better than a high carbohydrate diet.
Weight loss and insulin resistance improved by branched-chain amino acids
Weight loss and improvement in insulin resistance naturally go hand in hand, and a study just published in the journal Diabetologia confirms that consumption of branched-chain amino acids (BCAAs) helps both. Isoleucine, leucine and valine are already known to promote muscle growth and repair, influence brain signaling for appetite and metabolic rate, help with burn recovery, and be remedial for autism when it includes genetic mutations in BCAA pathways.
Sweetened drinks cause muscles to prefer burning sugar to fat
Sweetened drinks cause muscles to prefer burning sugar to fat
Breaks in prolonged sitting reduce cardiovascular risk and obesity
Breaks in prolonged sitting reduce cardiovascular risk and obesity
Less frequent eating predicts greater weight gain in female adolescents
Less frequent eating predicts greater weight gain in female adolescents
Metabolic syndrome and high blood pressure can be helped by sleep apnea treatment
Metabolic syndrome and high blood pressure can be helped by sleep apnea treatment
Modest doses of resveratrol produce metabolic changes similar to caloric restriction
Modest doses of resveratrol produce metabolic changes similar to caloric restriction
Brazil nuts improve lipids, oxidative stress and blood vessel function in obese adolescents
Brazil nuts improve lipids, oxidative stress and blood vessel function in obese adolescents
Understanding obesity as an inflammatory condition
Understanding obesity as an inflammatory condition
Dietary macronutrient composition for weight loss and weight maintenance
Dietary macronutrient composition for weight loss and weight maintenance
The advantages of intermittent versus continuous calorie restriction for long term weight loss
The advantages of intermittent versus continuous calorie restriction for long term weight loss
Dairy reduces inflammation and oxidative stress in metabolic syndrome
Dairy reduces inflammation and oxidative stress in metabolic syndrome