FUNCTIONAL MEDICINE BLOG 

Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.

Mood disorders and thyroid autoimmunity

Mood disorders and thyroid autoimmunity are linked by aberrant levels of hematopoietic/neuronal growth factors...even before hypothyroidism has developed, and also in relatives of thyroid autoimmunity subjects, growth factors necessary for healthy brain function are at levels associated with a range of mood disorders including bipolar, depression and psychosis. They also include an important reminder that antibodies can predict clinical disease years in advance.

Read More

Neuropsychiatric illness in non-celiac gluten sensitivity

Neuropsychiatric illness can result from neuroinflammation due to a variety of causes. Recent studies offer more evidence that depression and other neuropsychiatric disorders can be a manifestation of non-celiac gluten sensitivity. A paper published in Gastroenterology Research and Practice explores the pathophysiologic mechanisms by which gluten sensitivity can present as a variety of neuropsychiatric conditions in the absence of celiac disease.

Read More

Adolescent decline in verbal ability can predict psychosis in adulthood

It's well recognized that cognitive deficits in childhood or adolescence typically precede the onset of psychosis, but the studies done up until now have not determined whether the association is prodromal (an early symptom of psychosis itself) or neurodevelopmental (problems with brain development and maturation that set the stage for later psychosis). A study just published in JAMA Psychiatry offers strong evidence that verbal decline in adolescence reflects neurodevelopmental defects that significantly increase the lifetime risk for psychosis.

Read More