Insulin resistance and colorectal cancer

Two papers have been recently published documenting the link between insulin resistance and colorectal cancer. Insulin was higher and adiponectin (see forthcoming posts) lower with colorectal cancer, and both correlated with the stage of the disease according to the study published in the journal Colorectal Disease. The authors of the second paper published in the World Journal of Gastroenterology state: "In addition to cardiovascular disease, individual components of the metabolic syndrome have been linked to the development of cancer, particularly to colorectal cancer...The physiopathological mechanism that links metabolic syndrome and colorectal cancer is mostly related to abdominal obesity and insulin resistance." There has been a lot written about screening for colorectal cancer; I'm sure you can appreciate the implications of these papers for prevention.