FUNCTIONAL MEDICINE BLOG 

Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.

Four factors shown to predict long COVID
Dr. Jonathan Miller Dr. Jonathan Miller

Four factors shown to predict long COVID

There are four PASC (‘long COVID’)-anticipating biological factors that can be measured as early as at initial COVID-19 diagnosis, including pre-existing type 2 diabetes, SARS-CoV-2 RNAemia, EBV viremia, and autoantibodies from patients’ blood. These can help guide the prevention and treatment of long COVID.

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Systemic inflammation drives brain neurodegeneration

n a richly valuable paper published recently in Frontiers in Cellular Neuroscience the authors describe the ways in which systemic inflammation causes neurodegeneration in the brain associated with cognitive decline and a host of neuropsychiatric disorders. In the short term this manifests the anorexia, malaise, depression, and decreased physical activity known as sickness behavior (SB) that occurs with inflammation due to infection. Permanent cognitive and behavioral changes due to neurodegeneration occur when inflammation is chronic. Discerning and targeting the causes of inflammation offers opportunities for treatment.

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Autoimmune Autoimmune

Acute gastrointestinal infection can turn on autoimmune disorders

Autoimmune disorders can be promoted by a variety of factors that must be considered in case management.Acute gastrointestinal infection—such as a food-borne illness or viral gastroenteritis—can cause the immune system to lose tolerance for commensal bacteria (the ones that normally live in the intestines), contributing to the development of autoimmune disorders.

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