8/30/16 8/30/16

Leaky gut: inflammation, chronic fatigue and depression

Leaky gut permits bacterial LPS translocation into the gut lymphoid tissue where it triggers inflammation causing chronic fatigue and depression.

12/10/15 12/10/15

Depression, inflammation and light therapy

Research shows relief from depression by combining management of inflammation with bright light and chronotherapy to correct circadian dysregulation.

10/8/14 10/8/14

Nuts reduce inflammation and all-cause mortality

In the absence of allergy, the evidence supports the consumption of nuts as wholesome foods with anti-inflammatory and metabolic benefits, exactly what paleo diets intend to accomplish.

10/2/14 10/2/14

Lung cancer, inflammation, and tumor microenvironment

Lung cancer is the leading cause of cancer deaths worldwide. As with all other cancers, untangling the role of systemic inflammation (cancer promoting) versus inflammation in the tumor microenvironment (cancer fighting) is of fundamental clinical importance. A welcome study just published in PLOS One (Public Library of Science) sheds light on this critical conundrum while including the aspect of nutritional status.

9/7/14 9/7/14

Nigella sativa, a true 'wonder medicine'?

Nigella sativa, also known as black cumin, produces seeds with a mind-boggling wealth of medicinal virtues. For colleagues and others who may not be familiar with the abundance of scientific evidence for the use of Nigella sativa seed extract in clinical practice, this selection of citations serves as an introduction to its wide range of indications.

2/27/14 2/27/14

Bipolar disorder and neuroinflammation

There is a massive amount of evidence supporting the importance of assessing and treating neuroinflammation in bipolar disorder and other neuropsychiatric illnesses. This makes necessarily the comprehensive examination of autoimmunity and its numerous underlying contributory causes.

11/17/13 11/17/13

Cognitive decline: major overlooked causes

Cognitive decline is fueled by that have not received adequate attention but have great practical, clinical significance.

10/31/13 10/31/13

Quercetin may protect against LPS-induced inflammation

Quercetin, a flavonoid compound known for its anti-inflammatory and anti-histamine properties, may help to prevent inflammation induced by reactions to lipopolysaccharides (LPS)...quercetin may help protect patients from autoimmune flare-ups while treating associated gut infections.

10/20/13 10/20/13

Metabolic health status and aging determined by inflammation, not weight

Metabolic health is not reliably determined by weight or BMI (body mass index). Lean individuals can suffer from cardiovascular and other diseases involving metabolism, and evidence has been mounting that supports the notion of a subtype of obesity that is metabolically healthy. Inflammation can determine metabolic health in both obese and non-obese populations.

8/22/13 8/22/13

Autoimmune inflammation can elevate serum 1,25-dihydroxy vitamin D

I have found that patients with an autoimmune component to their case often have elevated 1,25-dihydroxy vitamin D (calcitriol). This is not the 25-hydroxy vitamin D3 (cholecalciferol metabolite) that we always test to determine vitamin D3 sufficiency. Often with normal and even low vitamin D3 levels, patients with various degrees of active autoimmunity are testing for elevated 1,25-dihydroxy vitamin D levels. Now research published in PLOS One (Public Library of Science) shows how autoimmune inflammation and elevated 1,25-dihydroxy vitamin D are associated.

5/16/13 5/16/13

Depression, aging and brain inflammation: indications for sustainable treatment

Depression and aging, not only diminished cognitive function but the level of physiological competence throughout the body, have brain inflammation in common. This fact is of premiere importance when designing rational treatment plans for both depression and high functioning longevity.