FUNCTIONAL MEDICINE BLOG
Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.
Thyroid autoimmunity and iron deficiency in pregnancy
Thyroid autoimmunity and iron deficiency are linked in pregnancy, posing a risk for numerous adverse fetal and maternal outcomes, including miscarriage.
Mood disorders and thyroid autoimmunity
Mood disorders and thyroid autoimmunity are linked by aberrant levels of hematopoietic/neuronal growth factors...even before hypothyroidism has developed, and also in relatives of thyroid autoimmunity subjects, growth factors necessary for healthy brain function are at levels associated with a range of mood disorders including bipolar, depression and psychosis. They also include an important reminder that antibodies can predict clinical disease years in advance.
Thyroid hormone conversion affects hypothyroid treatment
Dosing strategies solely based on a TSH definition of euthyroidism neglect the important role of FT3, which has recently emerged as an equally significant parameter in defining thyroid physiology... in cases where an FT3–FT4 dissociation becomes increasingly apparent following dose escalation of l-T4, an alternate treatment modality, possibly T3/T4 combination therapy, should be considered.
Low-normal thyroid function and cardiometabolic disorders
Observational studies suggest that low-normal thyroid function may be implicated in the pathogenesis of CVD. Low-normal thyroid function could also play a role in the development of MetS, insulin resistance and CKD...
Thyroid autoimmunity affects cognitive and emotional function
Autoimmune thyroiditis is "associated with cognitive and affective disorders also in the euthyroid [normal thyroid hormone level] state. Thereby thyroid antibodies might play a direct role or indicate an autoimmune process."
Thyroid in heart, metabolism, brain, kidney; vital importance of T3
Thyroid disorders have widespread impact and although subclinical hypothyroidism and low triiodothyronine (T3) syndrome are common they are frequently overlooked in practice.
Cognitive impairment associated with low but still 'normal' TSH
A study just published JCEM (The Journal of Clinical Endocrinology & Metabolism) offers evidence that TSH (thyroid stimulating hormone) levels when low but still 'normal' are associated with cognitive impairment and dementia.
Low 'normal' free T3 thyroid hormone predicts death in older patients even without overt hypothyroid
Low free T3 thyroid hormone (triiodothyronine, FT3), even without overt hypothyroid and still within most 'normal' reference ranges, predicts death from cardiovascular disease and all causes in people over 65 according to a study just published in The Journal of Clinical Endocrinology & Metabolism.
Anemia and thyroid hormones
In the present study significant associations between free T4 and erythrocyte indices, including haemoglobin concentration, haematocrit and erythrocyte count were demonstrated.
Anemia due to hypothyroid
Even subclinical hypothyroid (reduced systemic thyroid effect despite normal lab results) has far-reaching consequences because the ability of every cell in the body to do its work is diminished. A study just published in the European Journal of Internal Medicine further confirms that hypothyroid can be a cause of anemia.
How the Microbiome causes Autoimmune Dysfunction
How the Microbiome causes Autoimmune Dysfunction
The important role of autoimmunity in cardiovascular disease
The important role of autoimmunity in cardiovascular disease
Radiation protection and iodine supplementation
Radiation protection and iodine supplementation