8/30/16 8/30/16

Leaky gut: inflammation, chronic fatigue and depression

Leaky gut permits bacterial LPS translocation into the gut lymphoid tissue where it triggers inflammation causing chronic fatigue and depression.

10/11/14 10/11/14

Fatigue commonly caused by iron deficiency without anemia

Fatigue, often accompanied by depression and anxiety, frequently has iron deficiency shown by suboptimal levels of serum ferritin but occurring without anemia. This often goes unrecognized in clinical practice.

2/27/14 2/27/14

Bipolar disorder and neuroinflammation

There is a massive amount of evidence supporting the importance of assessing and treating neuroinflammation in bipolar disorder and other neuropsychiatric illnesses. This makes necessarily the comprehensive examination of autoimmunity and its numerous underlying contributory causes.

11/4/12 11/4/12

Lyme disease, neuropsychiatric symptoms and autoimmunity

As with other chronic infections, the most devastating effects of Lyme disease can occur from the immune system losing tolerance for normal tissue as it cross-reacts while attacking the pathogen. A paper just published in The Open Neurology Journal reviews the body of knowledge on the neuropsychiatric symptoms of Lyme disease and other infections as an immune mediated neurodegenerative disorder, enlarged by a wealth of citations.