FUNCTIONAL MEDICINE BLOG 

Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.

Oncology Oncology

Test helps select most effective chemotherapy for leukemia and other cancers

Acute myelocytic leukemia responds significantly better to chemotherapy selected by a test that shows the ability of each chemotherapeutic agent to induce apoptosis (cell death) according to research just published in the journal Leukemia & Lymphoma. This joins the list of other malignancies including breast cancer, ovarian cancer and endometrial cancer that are treated more effectively with chemotherapy screened by the microculture kinetic (MiCK) drug-induced apoptosis assay.

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Psychological harm of false-positive mammography persists for years

Apart from the controversy over the timing and frequency of screening mammography, practitioners must bear in mind that the psychological effects of false-positive findings can last for years and be as psychologically disturbing as a confirmed diagnosis of breast cancer. A study just published in Annals of Family Medicine confirms long lasting psychosocial harm from false-positive mammography results.

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Insulin resistance is a risk factor for breast cancer even with normal fasting glucose and insulin

Well before fasting glucose and insulin rise out of the normal range, background surges of insulin associated with decreased insulin receptor sensitivity do harm throughout the body and, as confirmed by a study just published in the Journal of Experimental & Clinical Cancer Research shows, promote breast cancer.

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High homocysteine is a risk factor for colorectal cancer

Colorectal cancer can be added to the list of conditions for which high levels of homocysteine are a risk factor according to a study recently published in The American Journal of Clinical Nutrition. Perhaps more important than the association of high homocysteine with low levels of vitamins B12, B6 or folate is the fact that homocysteine is a biomarker for inflammation.

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Autoimmune, Oncology Autoimmune, Oncology

Lymphoma and autoimmunity

Lymphoma and other hematologic malignancies ('blood cancers') have been shown be previous investigators to be linked to autoimmunity. The authors of a paper just published in the Journal of Autoimmunity illustrate how epigenetic mechanisms can imbalance immune function in a way that contributes to both autoimmunity and hematologic malignancies such has lymphoma, leukemia, etc.

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