FUNCTIONAL MEDICINE BLOG
Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.
Breast cancer risk doubles with calcium channel blockers for hypertension
Breast cancer risk assessment must take into consideration chronic inflammation, which comes to the fore in light of a study just published in JAMA Internal Medicine (formerly Archives of Internal Medicine) offering evidence that use use of calcium channel blockers double the risk for breast cancer.
Breast cancer in younger patients worse with iron deficiency
Iron deficiency may be an important and treatable risk factor that contributes to breast cancer in premenopausal patients.
Biopsy of breast tumors may spread cancer cells through the acute inflammatory response
A study just published in the journal Breast Cancer Research and Treatment demonstrates that it is possible for tumor cells to be spread by the acute inflammatory response to the biopsy procedure. Happily, the authors also show that anti-inflammatory treatment prior to the biopsy can protect against metastasis.
Test helps select most effective chemotherapy for leukemia and other cancers
Acute myelocytic leukemia responds significantly better to chemotherapy selected by a test that shows the ability of each chemotherapeutic agent to induce apoptosis (cell death) according to research just published in the journal Leukemia & Lymphoma. This joins the list of other malignancies including breast cancer, ovarian cancer and endometrial cancer that are treated more effectively with chemotherapy screened by the microculture kinetic (MiCK) drug-induced apoptosis assay.
Psychological harm of false-positive mammography persists for years
Apart from the controversy over the timing and frequency of screening mammography, practitioners must bear in mind that the psychological effects of false-positive findings can last for years and be as psychologically disturbing as a confirmed diagnosis of breast cancer. A study just published in Annals of Family Medicine confirms long lasting psychosocial harm from false-positive mammography results.
Insulin resistance is a risk factor for breast cancer even with normal fasting glucose and insulin
Well before fasting glucose and insulin rise out of the normal range, background surges of insulin associated with decreased insulin receptor sensitivity do harm throughout the body and, as confirmed by a study just published in the Journal of Experimental & Clinical Cancer Research shows, promote breast cancer.
High homocysteine is a risk factor for colorectal cancer
Colorectal cancer can be added to the list of conditions for which high levels of homocysteine are a risk factor according to a study recently published in The American Journal of Clinical Nutrition. Perhaps more important than the association of high homocysteine with low levels of vitamins B12, B6 or folate is the fact that homocysteine is a biomarker for inflammation.
Breast cancer inhibited by pomegranate juice
Pomegranate juice inhibits the growth and migration of breast cancer cells as well as preventing prostate cancer metastasis.
Colorectal tumor risk is reduced by magnesium
A study just published in The American Journal of Clinical Nutrition offers evidence that higher intakes of magnesium reduce colorectal tumor risk.
Lymphoma and autoimmunity
Lymphoma and other hematologic malignancies ('blood cancers') have been shown be previous investigators to be linked to autoimmunity. The authors of a paper just published in the Journal of Autoimmunity illustrate how epigenetic mechanisms can imbalance immune function in a way that contributes to both autoimmunity and hematologic malignancies such has lymphoma, leukemia, etc.
Breast cancer risk increased by diagnostic radiation
Breast cancer risk increased is by diagnostic radiation including mammography for BRCA1/2 gene carriers.
Breast cancer in Marin linked to vitamin D receptor differences
The high incidence of breast cancer in Marin County, California is linked to vitamin D receptor polymorphisms ('versions').
Prostate cancer treatment can make tumor cells resistant to therapy
Prostate cancer treatment can make tumor cells more resistant to therapy by changing their genetic expression.
Chronic immune stimulation of autoimmunity can trigger leukemia
Chronic immune stimulation of autoimmunity can trigger leukemia
High glycemic load is a risk factor for some breast cancers
High glycemic load is a risk factor for some breast cancers
Elevated blood sugar is associated with colorectal cancer in postmenopausal women
Elevated blood sugar is associated with colorectal cancer in postmenopausal women