FUNCTIONAL MEDICINE BLOG
Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.
Leaky gut: inflammation, chronic fatigue and depression
Leaky gut permits bacterial LPS translocation into the gut lymphoid tissue where it triggers inflammation causing chronic fatigue and depression.
Migraine, depression, Alzheimer's and lipid metabolism
"Taken together, our findings suggest it is possible that migraine is a neurologic disorder of 'minor' sphingolipid dysmetabolism..."
Stunning discovery links brain and immune system
Investigators report in the prestigious journal Nature the stunning discovery of a central nervous system lymphatic system connecting the brain and immune system.
Systemic inflammation drives brain neurodegeneration
n a richly valuable paper published recently in Frontiers in Cellular Neuroscience the authors describe the ways in which systemic inflammation causes neurodegeneration in the brain associated with cognitive decline and a host of neuropsychiatric disorders. In the short term this manifests the anorexia, malaise, depression, and decreased physical activity known as sickness behavior (SB) that occurs with inflammation due to infection. Permanent cognitive and behavioral changes due to neurodegeneration occur when inflammation is chronic. Discerning and targeting the causes of inflammation offers opportunities for treatment.
Nigella sativa, a true 'wonder medicine'?
Nigella sativa, also known as black cumin, produces seeds with a mind-boggling wealth of medicinal virtues. For colleagues and others who may not be familiar with the abundance of scientific evidence for the use of Nigella sativa seed extract in clinical practice, this selection of citations serves as an introduction to its wide range of indications.
Cognitive decline: major overlooked causes
Cognitive decline is fueled by that have not received adequate attention but have great practical, clinical significance.
The advantages of intermittent versus continuous calorie restriction for long term weight loss
The advantages of intermittent versus continuous calorie restriction for long term weight loss
Acetyl-L-carnitine protects the brain from alcohol-induced damage
Acetyl-L-carnitine protects the brain from alcohol-induced damage
Inflammation, mitochondrial dysfunction and neurodegeneration in major depression
Inflammation, mitochondrial dysfunction and neurodegeneration in major depression
Loss of smell can be an early sign of Parkinson's Disease
Loss of smell can be an early sign of Parkinson's Disease
Adolescence, a dangerous time for alcohol excess—but so is anytime
Adolescence, a dangerous time for alcohol excess—but so is anytime
The common danger of delirium and dementia after surgery, and pre-existing neurodegeneration
The common danger of delirium and dementia after surgery, and pre-existing neurodegeneration
Neuroinflammation plays a crucial role in neurodegenerative diseases
Neuroinflammation plays a crucial role in neurodegenerative diseases
Lying obliquely is a clinical sign of cognitive impairment
Lying obliquely is a clinical sign of cognitive impairment