10/30/18 10/30/18

Systemic thyroid hormone effects with levothyroxine can fall short

Systemic thyroid hormone status—the systemic effects of thyroid hormone activity—has been further confirmed to be insufficient with levothyroxine therapy in a significant percentage of cases, even though laboratory levels of TSH and T4 are normalized...

10/5/17 10/5/17

TSH elevation associated with pregnancy problems

TSH (thyroid stimulating hormone) when elevated even within the 'normal' range at preconception, can result in adverse pregnancy outcomes.

11/25/16 11/25/16

Thyroid disorders in children and adolescents: clinical review

5/12/16 5/12/16

Mood disorders and thyroid autoimmunity

Mood disorders and thyroid autoimmunity are linked by aberrant levels of hematopoietic/neuronal growth factors...even before hypothyroidism has developed, and also in relatives of thyroid autoimmunity subjects, growth factors necessary for healthy brain function are at levels associated with a range of mood disorders including bipolar, depression and psychosis. They also include an important reminder that antibodies can predict clinical disease years in advance.

11/23/15 11/23/15

Thyroid hormone conversion affects hypothyroid treatment

Dosing strategies solely based on a TSH definition of euthyroidism neglect the important role of FT3, which has recently emerged as an equally significant parameter in defining thyroid physiology... in cases where an FT3–FT4 dissociation becomes increasingly apparent following dose escalation of l-T4, an alternate treatment modality, possibly T3/T4 combination therapy, should be considered.

3/16/15 3/16/15

Low-normal thyroid function and cardiometabolic disorders

Observational studies suggest that low-normal thyroid function may be implicated in the pathogenesis of CVD. Low-normal thyroid function could also play a role in the development of MetS, insulin resistance and CKD...

4/6/14 4/6/14

Thyroid in heart, metabolism, brain, kidney; vital importance of T3

Thyroid disorders have widespread impact and although subclinical hypothyroidism and low triiodothyronine (T3) syndrome are common they are frequently overlooked in practice.

11/7/13 11/7/13

Low 'normal' free T3 thyroid hormone predicts death in older patients even without overt hypothyroid

Low free T3 thyroid hormone (triiodothyronine, FT3), even without overt hypothyroid and still within most 'normal' reference ranges, predicts death from cardiovascular disease and all causes in people over 65 according to a study just published in The Journal of Clinical Endocrinology & Metabolism.

9/19/13 9/19/13

Progesterone increases thyroid hormone

This 12-week randomized controlled progesterone trial documented that Free T4 levels were significantly elevated in progesterone-treated compared with placebo-treated women.

9/10/13 9/10/13

Autism and autoimmunity: more evidence

4/25/13 4/25/13

Anemia and thyroid hormones

In the present study significant associations between free T4 and erythrocyte indices, including haemoglobin concentration, haematocrit and erythrocyte count were demonstrated.

3/1/13 3/1/13

Study associates iodine deficiency with type 2 diabetes

Astute clinicians are cautious with iodine supplementation due to the risk for triggering latent thyroid autoimmunity, but a study just published in the journal Experimental and Clinical Endocrinology & Diabetes is a reminder to remain vigilant about the potential need for iodine when managing type 2 diabetes.