FUNCTIONAL MEDICINE BLOG
Includes over 800 monographs reporting on emerging studies in the medical and scientific literature of practical clinical importance, easily searched for content.
CKD (chronic kidney disease) expected for 50% over age 30
Chronic kidney disease incidence is rising steeply and projected to affect half the population aged 30 to 64. Key causal factors are metabolic syndrome with insulin resistance and hypertension. These are made worse by added sugars than by salt.
Hair loss frequently associated with autoimmunity
Identifying hair loss as associated with early immune system dysregulation not only permits proper treatment of the presenting complaint but becomes an opportunity to ward off progression to more debilitating autoimmune disease.
Nuts reduce inflammation and all-cause mortality
In the absence of allergy, the evidence supports the consumption of nuts as wholesome foods with anti-inflammatory and metabolic benefits, exactly what paleo diets intend to accomplish.
Lung cancer, inflammation, and tumor microenvironment
Lung cancer is the leading cause of cancer deaths worldwide. As with all other cancers, untangling the role of systemic inflammation (cancer promoting) versus inflammation in the tumor microenvironment (cancer fighting) is of fundamental clinical importance. A welcome study just published in PLOS One (Public Library of Science) sheds light on this critical conundrum while including the aspect of nutritional status.
Depression and brain inflammation
Evidence for the role of brain inflammation in depression is proliferating as noted in a report published recently in JAMA. Certain biomarkers including the proinflammatory cytokines interleukin-6 (IL-6) and TNF, and CRP are standing out...
Cognitive decline: major overlooked causes
Cognitive decline is fueled by that have not received adequate attention but have great practical, clinical significance.
Quercetin may protect against LPS-induced inflammation
Quercetin, a flavonoid compound known for its anti-inflammatory and anti-histamine properties, may help to prevent inflammation induced by reactions to lipopolysaccharides (LPS)...quercetin may help protect patients from autoimmune flare-ups while treating associated gut infections.
Metabolic health status and aging determined by inflammation, not weight
Metabolic health is not reliably determined by weight or BMI (body mass index). Lean individuals can suffer from cardiovascular and other diseases involving metabolism, and evidence has been mounting that supports the notion of a subtype of obesity that is metabolically healthy. Inflammation can determine metabolic health in both obese and non-obese populations.
Biopsy of breast tumors may spread cancer cells through the acute inflammatory response
A study just published in the journal Breast Cancer Research and Treatment demonstrates that it is possible for tumor cells to be spread by the acute inflammatory response to the biopsy procedure. Happily, the authors also show that anti-inflammatory treatment prior to the biopsy can protect against metastasis.
Depression, aging and brain inflammation: indications for sustainable treatment
Depression and aging, not only diminished cognitive function but the level of physiological competence throughout the body, have brain inflammation in common. This fact is of premiere importance when designing rational treatment plans for both depression and high functioning longevity.
Coronary artery inflammation is reduced by coenzyme Q10
Coronary artery inflammation is reduced by coenzyme Q10
Magnesium, inflammation, insulin resistance and diabetes
Magnesium, inflammation, insulin resistance and diabetes
Magnesium deficiency and death from cardiovascular disease
Magnesium deficiency and death from cardiovascular disease
Pro-inflammatory cytokines of rheumatoid arthritis reduced by Vitamin B6
Pro-inflammatory cytokines of rheumatoid arthritis reduced by Vitamin B6
The autoimmune aspect of cardiovascular disease and Th17/Treg imbalance
The autoimmune aspect of cardiovascular disease and Th17/Treg imbalance
Inflammation and insulin resistance genes are activated by surgery
Inflammation and insulin resistance genes are activated by surgery
Just seeing someone who is sick can increase proinflammatory cytokines
Just seeing someone who is sick can increase proinflammatory cytokines
Nervous system regulation of inflammation, cytokines, and heart rate variability
Nervous system regulation of inflammation, cytokines, and heart rate variability