Dr. Jonathan Miller 7/29/22 Dr. Jonathan Miller 7/29/22

Telomere dysfunction without shortening also drives immunosenescence

Oxidative damage can rapidly cause telomeres to no longer function, resulting in the ‘zombie cells’ characteristic of immunosenescence—in the absence of shortening.

11/6/18 11/6/18

Pregnancy induced hypertension often requires selenium

5/5/15 5/5/15

Breast cancer, oxidative stress and NF-κB

A paper just published in the journal Breast Cancer Research and Treatment highlights how reactive oxygen species (ROS) activate pro-inflammatory NF-κB (nuclear factor kappa beta, also an oncogenic transcription factor) to promote more aggressive breast cancer, and that this can be ameliorated by NAC.

4/2/15 4/2/15

ALS treatment: start long before clinical symptoms

ALS (amyotrophic lateral sclerosis) has a long presymptomatic period during which neuroprotective interventions can be applied.

3/23/15 3/23/15

Blood from children with autism induces autistic features in rats

"One of the most remarkable findings of the current study is the development of several features of autism in young rats whose brains were exposed to sera from autistic children...Remarkably, P6 treatment was able to rescue these structural abnormalities probably via increased BDNF expression."

10/8/14 10/8/14

Nuts reduce inflammation and all-cause mortality

In the absence of allergy, the evidence supports the consumption of nuts as wholesome foods with anti-inflammatory and metabolic benefits, exactly what paleo diets intend to accomplish.

2/27/14 2/27/14

Bipolar disorder and neuroinflammation

There is a massive amount of evidence supporting the importance of assessing and treating neuroinflammation in bipolar disorder and other neuropsychiatric illnesses. This makes necessarily the comprehensive examination of autoimmunity and its numerous underlying contributory causes.